[10] Iowa State 11-14 Kansas [3] 2022-06-05 21:30
Stadium: David Booth Memorial Stadium (Lawrence, KS) Round: 1
Home Manager: Matt Campbell Away Manager: Lance Leipold
Head to Head
| NCAAF | 2021/10/02 23:00 | Kansas v Iowa State | W | 7-59 |
| NCAAF | 2020/10/31 16:00 | Iowa State v Kansas | W | 52-22 |
| NCAAF | 2019/11/23 17:00 | Kansas v Iowa State | W | 31-41 |
| NCAAF | 2018/11/03 16:00 | Iowa State v Kansas | W | 27-3 |
| NCAAF | 2017/10/14 16:00 | Kansas v Iowa State | W | 0-45 |
| NCAAF | 2016/11/12 17:00 | Iowa State v Kansas | W | 31-24 |
| NCAAF | 2015/10/03 16:00 | Iowa State v Kansas | W | 38-13 |
| NCAAF | 2014/11/08 20:30 | Kansas v Iowa State | L | 34-14 |
Home History
| NCAAF Bowl Games | 2021/12/29 22:45 | Iowa State v Clemson | L | 13-20 |
| NCAAF | 2021/11/26 21:30 | TCU v Iowa State | W | 14-48 |
| NCAAF | 2021/11/20 17:00 | Iowa State v Oklahoma | L | 21-28 |
| NCAAF | 2021/11/13 20:30 | Iowa State v Texas Tech | L | 38-41 |
| NCAAF | 2021/11/06 23:30 | Texas v Iowa State | W | 7-30 |
| NCAAF | 2021/10/30 18:00 | Iowa State v West Virginia | L | 31-38 |
| NCAAF | 2021/10/23 19:30 | Oklahoma State v Iowa State | W | 21-24 |
| NCAAF | 2021/10/16 23:30 | Iowa State v Kansas State | W | 33-20 |
Away History
| NCAAF | 2021/11/28 00:00 | West Virginia v Kansas | L | 34-28 |
| NCAAF | 2021/11/20 21:00 | Kansas v TCU | L | 28-31 |
| NCAAF | 2021/11/14 00:30 | Kansas v Texas | W | 57-56 |
| NCAAF | 2021/11/06 16:00 | Kansas State v Kansas | L | 35-10 |
| NCAAF | 2021/10/30 23:00 | Kansas v Oklahoma State | L | 3-55 |
| NCAAF | 2021/10/23 16:00 | Oklahoma v Kansas | L | 35-23 |
| NCAAF | 2021/10/16 20:00 | Texas Tech v Kansas | L | 41-14 |
| NCAAF | 2021/10/02 23:00 | Kansas v Iowa State | L | 7-59 |
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