| WNCAAB | 11/20 00:30 | - | Nicholls State (W) vs Mississippi Valley State (W) | - | View | |
| WNCAAB | 11/22 20:00 | - | Southern Miss Women vs Nicholls State (W) | - | View | |
| WNCAAB | 12/01 17:00 | - | Nicholls State Women vs Louisiana Christian Women | - | View | |
| WNCAAB | 12/17 00:30 | - | Nicholls State (W) vs Incarnate Word (W) | - | View | |
| WNCAAB | 12/19 00:30 | - | Nicholls State (W) vs Houston Christian (W) | - | View | |
| WNCAAB | 12/29 23:00 | - | Texas A&M Corpus Christi Women vs Nicholls State (W) | - | View |
| WNCAAB | 11/15 00:30 | - | UL Lafayette Women v Nicholls State (W) | W | 64-66 | |
| WNCAAB | 11/12 16:00 | - | [142] Nicholls State (W) v Basquete Curitaba U22 [1] | L | 64-89 | |
| WNCAAB | 11/09 02:00 | - | Nicholls State (W) v UTEP (W) | L | 61-76 | |
| WNCAAB | 11/04 00:00 | - | Alcorn State (W) v Nicholls State (W) | W | 66-72 | |
| WNCAAB | 03/11 18:30 | 3 | [139] Nicholls State Women v Stephen F. Austin Women [23] | L | 65-77 | |
| WNCAAB | 03/10 18:30 | 122 | [139] Nicholls State Women v UT Rio Grande Valley Women [178] | W | 55-53 | |
| WNCAAB | 03/01 20:00 | - | Stephen F. Austin Women v Nicholls State Women | L | 79-56 | |
| WNCAAB | 02/28 01:00 | - | Lamar Women v Nicholls State Women | L | 68-49 | |
| WNCAAB | 02/22 19:00 | - | Nicholls State Women v Kharchenko/ Njoze | L | 50-59 | |
| WNCAAB | 02/21 00:30 | - | Nicholls State (W) v Texas A&M Corpus Christi Women | L | 44-59 | |
| WNCAAB | 02/15 19:00 | - | [92] Nicholls State Women v Southeastern Louisiana Women [18] | L | 50-63 | |
| WNCAAB | 02/14 00:30 | - | New Orleans Women v Nicholls State Women | W | 59-72 |
The Nicholls Colonels women's basketball team represents Nicholls State University in Thibodaux, Louisiana, United States. The school's team currently competes in the Southland Conference, which is part of the National Collegiate Athletic Association's Division I. Nicholls' first women's basketball team was fielded in 1974–1975. The team plays its home games at 3,800-seat Stopher Gymnasium and are coached by Justin Payne.
Nicholls State has appeared in the NCAA Women's Division I Basketball Tournament once The Colonels have a 0–1 record.
| Year | Seed | Round | Opponent | Result |
|---|---|---|---|---|
| 2018 | #16 | First Round | #1 Mississippi State | L 50–95 |